Welcome to the Clinical Immunology Research Laboratory (CIRL) in the Department of Pathology and Laboratory Medicine at UCLA. The CIRL is part of the General Clinical Research Center Core Laboratory, serves as the Immunology Core Laboratory for the Multicenter AIDS Cohort Study and the Cousins Center for Psychoneuroimmunology at UCLA, and is the immunology reference laboratory for the hospital-based clinical laboratories at the UCLA Medical Center.

The CIRL provides state of the art immune-based testing at affordable prices in support of both clinical and translational studies for more than 20 years. The laboratory specializes in assays to evaluate lymphocyte function. Consultative services for study design and interpretation of immunological data are also available.

Services include processing and separation of mononuclear cells, preparation of cells for analysis, data analysis and specimen storage. Same day testing is performed for functional assays (natural killer cell cytotoxicity and lymphocyte proliferation) that are affected by overnight storage. A rigorous quality control program has been established to maintain consistent test results and reference intervals have been established for proper interpretation of test results. New tests are continuously being developing and implemented to meet the evolving needs of investigators.

The laboratory is a California licensed, CLIA-certified and College of American Pathologist accredited laboratory that is staffed by 10-full time research scientists. The facility works with investigators both inside and outside the UCLA enterprise on a collaborative and fee-for-service basis. There are currently more than 30 internally funded investigators utilizing the laboratory, with more than 7000 tests being performed on an annual basis.